Autoimmune Diseases

Immunoenzymatic assay (ELISA) for the quantitative determination of autoantibodies. Method on microplate (96 breakable wells), TMB

ANCA Vasculitis

Code	Item	Sensitivity	Specificity	Incubation time
DKO091	anti- PR-3 (c-ANCA)	100,0%	100,0%	60+35+15 min
DKO092	anti- MPO (p-ANCA)	100,0%	100,0%	60+35+15 min

Gastro Enterology

Code	Item	Sensitivity	Specificity	Incubation time
DKO106	Anti-Deamidated Gliadin Peptides (DGP) IgG	94,1%	100,0%	30+30+15 min
DKO107	Anti-Deamidated Gliadin Peptides (DGP) IgA	100,0%	97,6%	30+30+15 min
DKO108	Anti-Transglutaminase IgA (for export only)	88,5%	100,0%	30+30+15 min
DKO109	Anti-Transglutaminase IgG (for export only)	80,96%	100,0%	30+30+15 min
DKO140	Anti-Transglutaminase IgA			30+15+15+5 min
DKO141	Anti-Transglutaminase IgG			30+15+15+5 min

Thrombosis

Code	Item	Sensitivity	Specificity	Incubation time
DKO110	Anti-Beta2 Glycoprotein IgG	76,64%	95,83%	60+30+15 min
DKO111	Anti-Beta2 Glycoprotein IgM	82,35%	95,83%	60+35+15 min
DKO112	Anti-Cardiolipin IgM	83%	78%	60+60+15 min
DKO113	Anti-Cardiolipin IgG	75%	70%	60+60+15 min
DKO114	Anti-Phospholipid Screen	IgG 100% IgM90%	IgG 92,9% IgM 90%	60+30+15 min
DKO118	APS Specific Anticardiolipin/Vimentin IgG	76,8%	100%	60+60+15 min
DKO127	APS Specific Anticardiolipin/Vimentin IgM			60+60+15 min

Diabetes

Code	Item	Sensitivity	Specificity	Incubation time
DKO083	Anti-Insulin (IAA)	60%	90%	60+60+20+20 min
DKO084	Anti-IA2 (Protein Tyrosine Phosphastase)	75%	98%	O.N.+60+20+20 min
DKO082	Anti-GAD (Glutamic Acid Decarboxylase)	92,3%	98,6%	60+15+15 min
DKO123	Anti-Zn T8 (Anti Zn Transporter 8 antibody)	68%	99%	30+30+15 min

Thyroid

Code	Item	Sensitivity	Specificity	Incubation time
DKO116	Anti-TPO (Thyroid Peroxidase)	94%	92,9%	30+30+15 min
DKO115	Anti-TG (Thyreoglobulin)	96,3%	94,9%	30+30+15 min
DKO085	Anti-TSH Receptors	95%	100,0%	120+20+20+20 min

Rheumatology

Code	Item	Sensitivity	Specificity	Incubation time
DKO094	Anti-Centromer B	100%	97,8%	30+30+15 min
DKO095	Anti-ds DNA IgG (Double Standed DNA)	93.3%	95,2%	30+30+15 min
DKO096	Anti-SS-A (Sjögren\'s Syndrome A)	94,3%	94,6%	30+30+15 min
DKO097	Anti-SS-A (Sjögren\'s Syndrome B)	80%	98,2%	30+30+15 min
DKO098	Anti-ENA Screen (Exctractable Nuclear Antigen)	94,7%	92,3%	30+30+15 min
DKO099	Anti-ANA Screen (Antinuclear Antigen)	83,9%	100%	30+30+15 min
DKO100	Anti-Sm (Smith Antigen)	100%	98,4%	30+30+15 min
DKO101	Anti-Scl 70 (DNA Topoisomerase I)	100%	100%	30+30+15 min
DKO102	Anti-Jo1 (Histidyl-tRNA Synthetase)	90%	98,4%	30+30+15 min
DKO103	Anti-Histonen.a.	81,3%	100%	30+30+15 min
DKO104	Anti-RNP70 (Nuclear Ribonucleoprotein 70kDA)	100%	96,1%	30+30+15 min
DKO105	Anti-RNP/Sm (Nuclear Ribonucleoprotein 70kDA and Smith Antigen)	96,1%	100%	30+30+15 min
DKO117	Anti-CCP IgG	79%	97%	30+30+15 min
DKO119	ENA Profile	Sensitivity and specificity are the same as in the single antigen kiten kit
DKO129	MMP3 (Matrix Metalloproteinase-3)
DKO130	RF IgA (Rheumatoid Factor IgA)	77,8%	92,9%	60+30+10 min
DKO131	RF IgG (Rheumatoid Factor IgG)	83,4%	90,5%	60+30+10 min
DKO132	RF IgM (Rheumatoid Factor IgM)	91,4%	93,5%	60+30+10 min
DKO133	RF Screen (Rheumatoid Factor IgG+IgA+IgM)			60+30+10 min
DKO122	Anti IFI16			30+30+15 min