AmplideX FMR1 PCR Process Control

• Ready to use, well characterized Controls (number of CGG repeats or % methylation)
• A single control covering multiple size ranges in FMR1 gene (Normal (NOR), Pre Mutation (PM), Full Mutation (FM)
• Assessment of sizing resolution for alleles separated by 2 CGG (30,32)
• Amplification of low levels of FM alleles (10%) in presence of NOR and PM alleles (90%)

Product Description

The AmplideX^® FMR1 Controls are proprietary mixtures of genomic DNA containing multiple alleles. These well characterized controls can be used as process or batch controls covering multiple size ranges and different methylation states in the FMR1 gene.

Reference:

1. A Novel Methylation PCR that Offers Standardized Determination of FMR1 Methylation and CGG Repeat Length without Southern Blot Analysis. Grasso et. al. J Mol Diagn. In Press, Available online 29 Oct 2013