AmplideX PCR/CE SMN1 Kit
The AmplideX PCR/CE SMN1 Kit provides a rapid, robust, and reliable method for the quantification of SMN1 exon 7 copy number from whole blood and buccal samples. With its streamlined PCR/CE workflow, rapid turnaround time, and automated results reporting software, the assay provides a simple and scalable SMN1 solution for all laboratories.
Features & Benefits
AmplideX technology has become widely established for the detection and quantification of repeat expansions in a number of genes, including FMR1, C9orf72, and DMPK. With the AmplideX PCR/CE SMN1 Kit, this approach is applied to copy number resolution, allowing SMN1 exon 7 copy number to be estimated in under four hours using readily available laboratory equipment.
Reduced Complexity
· Similar workflow to the AmplideX FMR1 kit eases implementation and testing
· Scalable design allows for high-throughput testing
· Automated analysis objectively reports copy number
Optimized Workflow
· A simplified workflow compared to alternative methods
· Fully kitted solutions with fewer QC and pipetting steps
· DNA to data in under four hours with only 45 minutes of hands-on-time
Quality Performance
· Ability to differentiate between 0, 1, 2, 3 and > 3 copies
· Robust, reliable results with non-overlapping ratios for each copy number output
· Concordance with previously characterized samples
Analytical characteristics of AmplideX PCR/CE SMN1 Kit:
· Excellent concordance with previously characterized clinical samples
· Consistent results compared to other commercially available methods
· Automated results reporting via AmplideX Reporter software
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