Armored RNA Quant SARS-CoV-2
Armored technology is a system for producing robust, ribonuclease-resistant RNA controls and standards by assembling specific RNA sequences and viral coat proteins into pseudo-viral partcles.
The RNA can be extracted from the viral coat protein using the same methods used to extract test specimen RNA or by incubating at 75°C for 3 minutes to release the RNA from partcles.
Armored Controls have been utilized in IVD-approved assays for more than 20 years and continue to serve as an important tool in the rapidly evolving space of molecular diagnostics.
In response to the worldwide outbreak of COVID-19, Asuragen has developed a novel Armored RNA control that targets the SARS-CoV-2 viral nucleocapsid (N) region. Our new RNAse P construct aligns with the CDC and WHO recommended Diagnostic Panel (CDC-006-00019) providing a stable, reliable, and safe way to rapidly test for the presence of the novel Coronavirus.
Each control encodes an in vitro transcribed RNA encapsulated in a protective protein coat to create a virus-like particle resistant to nuclease degradation. This allows the products to be used as RNA extraction controls, process quality controls, or positive diagnostic reference controls.
From feasibility to clinical use, these robust and versatile controls are beneficial across all sectors of the research and diagnostic spectrum.
REDUCED COMPLEXITY
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Available as standalone catalog items
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High-quality solution to monitor extraction and process efficiency
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Compatible with a wide range of RNA-based clinical assays
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Non-infectious, synthetic constructs simplify shipping and storage
OPTIMIZED WORKFLOW
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Deployable as extractable, exogenous internal positive control
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Tailored sequences specific to SARS-CoV-2 and RNAse P
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Degradation resistant in majority of biological matrices
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Multiple volume and manufacturing options available
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Available as cGMP or development lot in a range of fill volumes
QUALITY PERFORMANCE
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Concentration determined using National Institute of Standards (NIST)traceable standard
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Highly standardized, quality controlled manufacturing ensures reliabilityand consistency between lots
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Manufactured in a cell-free system
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Prodotti per il mercato Italiano